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Liver Spots are Linked to Air Pollution

Liver spots develop on skin for a variety of reasons.  But, new evidence reported in a recent study published in the Journal of Investigative Dermatology shows that liver spots are affected by air-pollution, including traffic-related soot exposure.

The technical name for liver spots (commonly referred to as “age spots”) is lentigines.  Liver spots are dark areas that appear on the skin of light-skinned people.  They normally appear on the face, upper body, forearms, and hands.  In the United States, 90 percent of Caucasians near the age of 60, and 20 percent of light-skinned people younger than 35 years-old develop liver spots due to sun exposure.

Usually, liver spots — or age spots — start out small.  But after time, they become larger.  Normally, liver spots are brown in color, but they can also show up yellow-tan to black on a person’s skin.  Although some liver spots can be pre-cancerous, they are generally benign.

Liver Spots Linked To Air Pollution

This recent study of women from China and Germany, led by Dr. Jean Krutmann of the IUF-Leibniz Research Institute for Environmental Medicine in Dusseldorf, set out to investigate a possible link between air pollution and liver spots.

Before initiating this large study, Dr. Krutmann had already determined that skin is affected by air pollution.  Dr. Krutmann suggested that liver spots develop on the skin due to exposure to traffic-related soot and nitrogen dioxide, as well.  Nitrogen dioxide (NO2) has already been linked to lung cancer.  But prior to this most recent study, the effect of NO2 on human skin was vague.

Liver spots develop on faces of women exposed to nitrogen dioxide

Dr. Krutmann and his colleagues began their study to see if there’s a possible link between air pollution and liver spot, or lentigines.  They formed two groups of women — a Chinese group and a German group.

The Chinese group consisted of 743 Han Chinese women ranging from 28 to 70 years-old.  The average age of this group of women was 59.  Twenty percent of the women had a history of smoking.  The women spent an average of 3.5 hours a day exposed to the sun.  A little more than 4 percent of these women used cosmetics with sunscreen.

The German group of women consisted of 806 white females, with ages ranging from 67 to 80 years.  In this group, the average age was 73.5.  Twenty percent of these women had a history of smoking.

Both groups of women were exposed to nitrogen dioxide.  The researchers found that patches of liver spots, or lentigines, were found on the cheeks of both groups of women aged more than 50 years-old – with higher concentration of liver spots on the Asian women.  The results also showed the women did not necessarily get liver spots on the hands or forearms.

However, with increased doses of nitrogen dioxide, there was a 25 percent increase in lever spots on the female research subjects.  The team of researchers also found that concentrated levels of nitrogen dioxide gas had a higher effect on causing liver spots than traffic-related soot particles.

How to protect skin from air pollution

In an interview with Medical News Today, Dr. Krutmann offered the following advice to women on how to prevent getting liver spots.

“If you regularly clean your face, it’s very likely that you reduce the load of pollution on your skin, and thus you have less of a problem, and this is what we have also recommended.  The other thing is, if you have a good skin barrier, it’s much more difficult for the pollutants to penetrate.”

Dr. Krutmann added that ultraviolet filters should be developed to help protect against pollution.  Dr. Krutmann explains that air pollution contains carbon particles.  These carbon particles are covered by polyaromatic hydrocarbons.  Polyaromatic hydrocarbons dissolve in oil – which allows them to penetrate the outer layer of our skin, and then to individual skin cells.  Eventually, the hydrocarbons cause stress on the skin cells – causing them to oxidize.

Dr. Krutmann suggests there are some products that contain antioxidants that offer protection against air pollution and skin damage.  Additionally, some companies have put cosmetic ingredients in creams to provide the protection needed against pollution.

Ways to prevent age spots

The Mayo Clinic offers some tips on ways to prevent getting liver spots.  Limiting sun exposure is the primary key.

  • Avoid the sun between 10 a.m. and 3 p.m. The sun’s rays are most intense during this time.  So, try to schedule outdoor activities for other times of the day.
  • Use sunscreen. Fifteen to 30 minutes before going outdoors, apply a broad-spectrum sunscreen that provides protection from both UVA and UVB light.  Use a sunscreen with a sun-protection factor (SPF) of at least 30.  Apply sunscreen generously, and reapply every two hours.  Apply sunscreen more often if perspiring or swimming.
  • Cover up. For protection from the sun, wear a broad-brimmed hat, which provides more protection than does a baseball cap or golf visor.  Also, wear tightly woven clothing that covers legs and arms.  Consider wearing clothing designed to provide sun protection.  An ultraviolet protection factor (UPF) of 40 to 50 provides the best protection.

Home remedies to treat liver spots

According to the Mayo Clinic, many fade lotions and creams for lightening age spots are available in drug stores, department stores, and on the Internet.  Depending on how dark the spots are and how often you apply the cream, these creams, or lotions may improve the appearance of liver spots.  However, regular use over several weeks or months may be required to produce noticeable results.

When choosing an over-the-counter, nonprescription fade cream, select one that contains hydroquinone, glycolic acid, or kojic acid.  Please note that some products, especially those that contain hydroquinone, may cause skin irritation.

(Featured image courtesy of YouTube)

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